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Our contacts

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Phone:    (212) 555 55 00 or (212) 555 55 00

Adress:    Company LTD Street nr 100, 4536534, Chicago, US


Innovative, cost-effective, "best in class" solutions to pressing problems in the global medical industry.

CITOFEM for International Use

For information on Citofem presentations in the United States click below


Citofem is a liquid-based cytology pap smear kit used as a replacement for the conventional method of pap smear preparation for use in screening for the presence of atypical cervical cancer cells including its precursor lesions (low-grade Squamous Intraepithelial Lesions and high-grade Squamous Intraepithelial Lesions), as well as all other cytologic categories as defined by The Bethesda System for Reporting Cervical or Vaginal Cytologic Diagnoses.
 It is also suitable for detection of atypical cells from bucal, penile, throat, anal and many other cell samples.

Citofem versus Competing Products

1) Greater cell capture and better detection

Citofem´s kit includes the highest quality brush available for cell capture, particularly endocervical cells. . (Competitors use inferior brushes).
100% cell capture. The entire brush head is transferred into and maintained in the sample vial, ensuring complete cell capture. (Competitors dispose of theirs, with substantial sample material lost)
Citofem´s unique cell-preservative clarifies the cell nuclei. As soon as the sample brush enters the Citofem vial, biochemical action separates blood, mucous, and other material from the target cells and their nuclei.
Citofem´s unique Bioprep further clarifies and cleans the sample after centrifuging to provide a superior sample for the technologist.
A clearer sample reduces reading time and error. 100% cell capture reduces the probability of false negatives.
Citofem can demonstrate that its accuracy and precision are second to none in the liquid cytology market.

2) Longer Sample Viability

Citofem´s Bioprep maintains, uncontaminated, a high quality sample for follow up/confirmation or other tests, such as Viro-Safe (for the L1 Capsid Protein of high risk HPV strains) for 90 days with no special care. This eliminates the need (and cost) of taking additional patient samples.

3) Cubliq Liquid Cover Slip

Cubliq improves reading and eliminates glass cover slides.
Citofem´s Cubliq is a resin-based product that substitutes glass cover slides. Optically, Cubliq is virtually perfect and eliminates the optical distortion associated with glass, and the pressure of glass cover slips on the sample.

4) Xylene-free

Xylene is a toxic substance used as a standard component in competitors products. It is a regulated substance in most countries, as it presents significant nervous system risk to workers who are exposed on a regular basis. By eliminating xylene from Citofem:

Eliminates this risk to laboratory workers,
Reduces regulatory responsibility (no longer a reportable substance in the laboratory for regulatory purpose),
And eliminates a toxic substance that requires (under the laws of many countries) special waste management procedures.

5) Simplicity

Citofem is as simple as a pap smear with no additional equipment or knowledge required. A laboratory can switch from traditional pap smears or other cytology systems to Citofem from one day to the next, with no investment in equipment or special training.

6) Higher Throughput Speed

Citofem has a demonstrably faster throughput speed than most competitors, including leading brands' automated systems. This means that laboratories can perform more high quality tests based on their optimum batch size, using less technician time.

7) Flexibility

Citofem´s unique approach allows many different types of cytology samples to be processed and analyzed using the same product. Protocols are currently available for buccal, penile, skin, sputum and a variety of other tests.

Regulatory Support

Citofem and its components are listed or registered in major regulatory agencies in Europe, the Americas and many other countries.  All needed data and supporting documentation for distributors and laboratories can be provided upon request.  

Awards and Recognition

Citofem has received many scientific and innovation awards, including a Silver Medal at the 2012 World Invention Exposition (Geneva).


Citofem is sold as a 500-test kit, with the following materials:

  • 500 Citofem® cell preservation vials
  • 500 Rovers® Cervex-Brush® Combi
  • 504 Glass Slides with Frosted End
  • 1 Bottle of EA-50 Dye Solution (450 ml)
  • 1 Bottle of Orange-OG6 Dye Solution (450ml)
  • 1 Bottle of Hematoxilin Dye Solution (450 ml)
  • 1 Bottle of Citofem® Processing Solution (450 ml)
  • 1 Bottle of CUBLIQ® liquid coverslip preservative (200 ml)
  • 1 Product insert